Deoxyuridine

Deoxyuridine
Identifiers


CAS Number	951-78-0^Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:16450^N
ChEMBL	ChEMBL353955^N
ChemSpider	13118^Y
ECHA InfoCard	100.012.232
MeSH	Deoxyuridine
PubChem	640
UNII	W78I7AY22C^Y
InChI InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1^Y Key: MXHRCPNRJAMMIM-SHYZEUOFSA-N^Y InChI=1/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1 Key: MXHRCPNRJAMMIM-SHYZEUOFBK
SMILES O=C/1NC(=O)N(\C=C\1)[C@@H]2O[C@@H]([C@@H](O)C2)CO
Properties
Chemical formula	C₉H₁₂N₂O₅
Molar mass	228.202
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Deoxyuridine (dU) is a compound and a nucleoside. It is similar in chemical structure to uridine, but without the 2'-hydroxyl group.

Idoxuridine and Trifluridine are variants of deoxyuridine used as antiviral drugs. They are similar enough to be incorporated as part of DNA replication, but they possess side groups on the uracil component (an iodine and a CF₃ group, respectively), that prevent base pairing.

A known use of dU is as a precursor in the synthesis of Edoxudine.

Nucleic acid constituents

Ribonucleoside	Adenosine Guanosine 5-Methyluridine Uridine 5-Methylcytidine Cytidine Inosine Xanthosine Wybutosine

Deoxyribonucleoside	Deoxyadenosine Deoxyguanosine Thymidine Deoxyuridine Deoxycytidine Deoxyinosine Deoxyxanthosine

Nucleotide
(Nucleoside monophosphate)

Ribonucleotide	AMP GMP m⁵UMP UMP CMP IMP XMP

Deoxyribonucleotide	dAMP dGMP dTMP dUMP dCMP dIMP dXMP

Cyclic nucleotide	cAMP cGMP c-di-GMP cADPR

Nucleoside diphosphate

ATP GTP m⁵UTP UTP CTP ITP XTP

dATP dGTP dTTP dUTP dCTP dITP dXTP

This article is issued from Wikipedia - version of the 9/22/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.