TUBGCP5

Identifiers

TUBGCP5, GCP5, tubulin gamma complex associated protein 5

External IDs

MGI: 2178836 HomoloGene: 14172 GeneCards: TUBGCP5

Gene ontology
Molecular function	• microtubule binding • structural constituent of cytoskeleton • microtubule minus-end binding • gamma-tubulin binding
Cellular component	• cytoplasm • cytosol • centrosome • spindle pole • equatorial microtubule organizing center • microtubule organizing center • spindle pole body • gamma-tubulin ring complex • microtubule • cytoskeleton
Biological process	• centrosome duplication • interphase microtubule nucleation by interphase microtubule organizing center • mitotic spindle assembly • cytoplasmic microtubule organization • meiotic nuclear division • microtubule cytoskeleton organization • microtubule nucleation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


114791


233276

Ensembl


n/a


ENSMUSG00000033790

UniProt


Q96RT8


Q8BKN5

RefSeq (mRNA)


NM_001102610 NM_052903


NM_146190

RefSeq (protein)


NP_001096080.1 NP_443135.3


NP_666302.2

Location (UCSC)

Chr 15: 22.98 – 23.04 Mb

Chr 7: 55.79 – 55.83 Mb

PubMed search

^[1]

^[2]

Wikidata

View/Edit Human

View/Edit Mouse

Gamma-tubulin complex component 5 is a protein that in humans is encoded by the TUBGCP5 gene.^[3]^[4] It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Murphy SM, Preble AM, Patel UK, O'Connell KL, Dias DP, Moritz M, Agard D, Stults JT, Stearns T (Nov 2001). "GCP5 and GCP6: two new members of the human gamma-tubulin complex". Mol Biol Cell. 12 (11): 3340–52. doi:10.1091/mbc.12.11.3340. PMC 60259. PMID 11694571.
↑ "Entrez Gene: TUBGCP5 tubulin, gamma complex associated protein 5".

Bittel DC, Kibiryeva N, Butler MG (2006). "Expression of 4 genes between chromosome 15 breakpoints 1 and 2 and behavioral outcomes in Prader–Willi syndrome.". Pediatrics. 118 (4): e1276–83. doi:10.1542/peds.2006-0424. PMID 16982806.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Chai JH, Locke DP, Greally JM, et al. (2003). "Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.". Am. J. Hum. Genet. 73 (4): 898–925. doi:10.1086/378816. PMC 1180611. PMID 14508708.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Nagase T, Kikuno R, Ohara O (2002). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.". DNA Res. 8 (4): 179–87. doi:10.1093/dnares/8.4.179. PMID 11572484.

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TUBGCP5

See also

References

Further reading