TAX1BP1

TAX1BP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases TAX1BP1, CALCOCO3, T6BP, TXBP151, Tax1 binding protein 1
External IDs MGI: 1289308 HomoloGene: 4395 GeneCards: TAX1BP1
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

8887

52440

Ensembl

ENSG00000106052

ENSMUSG00000004535

UniProt

Q86VP1

Q3UKC1

RefSeq (mRNA)

NM_001079864
NM_001206901
NM_001206902
NM_006024

NM_025816

RefSeq (protein)

NP_001073333.1
NP_001193830.1
NP_001193831.1
NP_006015.4

NP_080092.2

Location (UCSC) Chr 7: 27.74 – 27.84 Mb Chr 6: 52.71 – 52.77 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Tax1-binding protein 1 is a protein that in humans is encoded by the TAX1BP1 gene.[3]

Interactions

TAX1BP1 has been shown to interact with TNFAIP3[4] and TRAF6.[5] TAX1BP1 binds to TNFAIP3 or TRAF6 and suppresses NF-kappaB transcriptional activation.

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. "Entrez Gene: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1".
  4. De Valck, D; Jin D Y; Heyninck K; Van de Craen M; Contreras R; Fiers W; Jeang K T; Beyaert R (July 1999). "The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases". Oncogene. ENGLAND. 18 (29): 4182–90. doi:10.1038/sj.onc.1202787. ISSN 0950-9232. PMID 10435631.
  5. Ling, L; Goeddel D V (August 2000). "T6BP, a TRAF6-interacting protein involved in IL-1 signaling". Proc. Natl. Acad. Sci. U.S.A. UNITED STATES. 97 (17): 9567–72. doi:10.1073/pnas.170279097. ISSN 0027-8424. PMC 16905Freely accessible. PMID 10920205.

Further reading


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