List of highways numbered 220

Route 220 or Highway 220 may refer to:

Canada

• Manitoba Provincial Road 220
• Newfoundland and Labrador Route 220
• Prince Edward Island Route 220
• Quebec Route 220
• Saskatchewan Highway 220

China

• China National Highway 220 (G220)

Japan

• Japan National Route 220

United States

• Interstate 220
• U.S. Route 220
• Arkansas Highway 220
• California State Route 220
• Connecticut Route 220
• Florida State Road 220 (former)
• Georgia State Route 220
• Hawaii Route 220
• Iowa Highway 220
• Kentucky Route 220
• Maine State Route 220
• Massachusetts Route 220
• Minnesota State Highway 220
• Montana Secondary Highway 220
• New Mexico State Road 220
• New York State Route 220
• Ohio State Route 220
• Oregon Route 220 (former)
• Tennessee State Route 220
• Texas State Highway 220
• Utah State Route 220 (former)
• Washington State Route 220 (former)
• Wyoming Highway 220