PyrR binding site

PyrR binding site
Predicted secondary structure and sequence conservation of PyrR
Identifiers
Symbol PyrR
Rfam RF00515
Other data
RNA type Cis-reg
Domain(s) Bacteria
SO 0000233

The PyrR binding site is an RNA element that is found upstream of a variety of genes involved in pyrimidine biosynthesis and transport.[1]

The RNA structure permits binding of PyrR protein which regulates pyrimidine biosynthesis in Bacillus subtilis. When the protein binds, a downstream terminator hairpin forms, repressing transcription of biosynthesis genes.[1]

References

  1. 1 2 Bonner, ER; D'Elia JN; Billips BK; Switzer RL (2001). "Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR". Nucleic Acids Res. 29 (23): 48514865. doi:10.1093/nar/29.23.4851. PMC 96680Freely accessible. PMID 11726695.

External links

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