PyrR binding site
PyrR binding site | |
---|---|
Predicted secondary structure and sequence conservation of PyrR | |
Identifiers | |
Symbol | PyrR |
Rfam | RF00515 |
Other data | |
RNA type | Cis-reg |
Domain(s) | Bacteria |
SO | 0000233 |
The PyrR binding site is an RNA element that is found upstream of a variety of genes involved in pyrimidine biosynthesis and transport.[1]
The RNA structure permits binding of PyrR protein which regulates pyrimidine biosynthesis in Bacillus subtilis. When the protein binds, a downstream terminator hairpin forms, repressing transcription of biosynthesis genes.[1]
References
- 1 2 Bonner, ER; D'Elia JN; Billips BK; Switzer RL (2001). "Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR". Nucleic Acids Res. 29 (23): 4851–4865. doi:10.1093/nar/29.23.4851. PMC 96680. PMID 11726695.
External links
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