Phospholipid:diacylglycerol acyltransferase
phospholipid:diacylglycerol acyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.3.1.158 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a phospholipid:diacylglycerol acyltransferase (EC 2.3.1.158) is an enzyme that catalyzes the chemical reaction
- phospholipid + 1,2-diacylglycerol lysophospholipid + triacylglycerol
Thus, the two substrates of this enzyme are phospholipid and 1,2-diacylglycerol, whereas its two products are lysophospholipid and triacylglycerol.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase. This enzyme is also called PDAT. This enzyme participates in glycerolipid metabolism.
References
- Stymne S; Stahl, U; Lenman, M; Banas, A; Lee, M; Sandager, L; Ronne, H; Stymne, S (2000). "Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants". Proc. Natl. Acad. Sci. U.S.A. 97 (12): 6487–92. doi:10.1073/pnas.120067297. PMC 18631. PMID 10829075.
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