POLR3C

POLR3C
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases POLR3C, RPC3, RPC62, polymerase (RNA) III subunit C
External IDs MGI: 1921664 HomoloGene: 38185 GeneCards: POLR3C
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

10623

74414

Ensembl

ENSG00000186141

ENSMUSG00000028099

UniProt

Q9BUI4

Q9D483

RefSeq (mRNA)

NM_001303456
NM_006468

NM_028925

RefSeq (protein)

NP_001290385.1
NP_006459.3

NP_083201.1

Location (UCSC) Chr 1: 145.82 – 145.84 Mb Chr 3: 96.71 – 96.73 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

DNA-directed RNA polymerase III subunit RPC3 is an enzyme that in humans is encoded by the POLR3C gene.[3][4][5]

Interactions

POLR3C has been shown to interact with GTF3C4.[6][7]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Wang Z, Roeder RG (Jun 1997). "Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation". Genes Dev. 11 (10): 1315–26. doi:10.1101/gad.11.10.1315. PMID 9171375.
  4. Hu P, Wu S, Sun Y, Yuan CC, Kobayashi R, Myers MP, Hernandez N (Oct 2002). "Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits". Mol Cell Biol. 22 (22): 8044–55. doi:10.1128/MCB.22.22.8044-8055.2002. PMC 134740Freely accessible. PMID 12391170.
  5. "Entrez Gene: POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)".
  6. Hsieh, Y J; Wang Z; Kovelman R; Roeder R G (Jul 1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III". Mol. Cell. Biol. UNITED STATES. 19 (7): 4944–52. ISSN 0270-7306. PMC 84305Freely accessible. PMID 10373544.
  7. Hsieh, Y J; Kundu T K; Wang Z; Kovelman R; Roeder R G (Nov 1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity". Mol. Cell. Biol. UNITED STATES. 19 (11): 7697–704. doi:10.1128/mcb.19.11.7697. ISSN 0270-7306. PMC 84812Freely accessible. PMID 10523658.
  8. Klopocki E, Schulze H, Strauss G, et al. (February 2007). "Complex inheritance pattern resembling autosomal recessive inheritance involving a microdeletion in thrombocytopenia-absent radius syndrome". Am. J. Hum. Genet. 80 (2): 232–40. doi:10.1086/510919. PMC 1785342Freely accessible. PMID 17236129.

Further reading


This article is issued from Wikipedia - version of the 8/12/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.