OR2A5

OR2A5
Identifiers
Aliases OR2A5, OR2A11P, OR2A26, OR2A8, OR7-138, OR7-141, olfactory receptor family 2 subfamily A member 5
External IDs MGI: 3030282 HomoloGene: 64846 GeneCards: OR2A5
Orthologs
Species Human Mouse
Entrez

393046

258270

Ensembl

ENSG00000221836

ENSMUSG00000043119

UniProt

Q96R48

n/a

RefSeq (mRNA)

NM_012365

NM_146273

RefSeq (protein)

NP_036497.1

n/a

Location (UCSC) Chr 7: 144.05 – 144.05 Mb Chr 6: 42.9 – 42.9 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2A5 is a protein that in humans is encoded by the OR2A5 gene.[3][4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
  4. 1 2 "Entrez Gene: OR2A5 olfactory receptor, family 2, subfamily A, member 5".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia - version of the 6/4/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.