List of highways numbered 122

Route 122 or Highway 122 may refer to:

Canada

• New Brunswick Route 122
• Prince Edward Island Route 122
• Quebec Route 122

Japan

• Japan National Route 122

United States

• U.S. Route 122 (former)
• Alabama State Route 122
• Arkansas Highway 122
• California State Route 122
• Connecticut Route 122
• Florida State Road 122
• Georgia State Route 122
• Illinois Route 122
• Indiana State Road 122 (former)
• Iowa Highway 122
• Louisiana Highway 122
• Maine State Route 122
• Maryland Route 122 (Security Blvd.)
• Massachusetts Route 122
  • Massachusetts Route 122A
• M-122 (Michigan highway)
• Minnesota State Highway 122 (former)
• Missouri Route 122
• New Hampshire Route 122
• New Jersey Route 122
• New Mexico State Road 122
• New York State Route 122
• North Carolina Highway 122
• Ohio State Route 122
• Rhode Island Route 122
• South Carolina Highway 122
• Tennessee State Route 122
• Texas State Highway 122 (proposed)
  • Texas State Highway Spur 122
• Utah State Route 122
• Vermont Route 122
• Virginia State Route 122
• Washington State Route 122
• West Virginia Route 122
• Wisconsin Highway 122