LYPLA1

LYPLA1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases LYPLA1, APT-1, APT1, LPL-I, LPL1, hAPT1, lysophospholipase I
External IDs MGI: 1344588 HomoloGene: 100781 GeneCards: LYPLA1
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

10434

18777

Ensembl

ENSG00000120992

ENSMUSG00000025903

UniProt

O75608
Q6IAQ1

P97823

RefSeq (mRNA)

NM_008866

RefSeq (protein)

NP_032892.1

Location (UCSC) Chr 8: 54.05 – 54.1 Mb Chr 1: 4.81 – 4.85 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Acyl-protein thioesterase 1 is an enzyme that in humans is encoded by the LYPLA1 gene.[3][4]

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms. The use of alternate polyadenylation sites has been found for this gene. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Wang A, Yang HC, Friedman P, Johnson CA, Dennis EA (Apr 1999). "A specific human lysophospholipase: cDNA cloning, tissue distribution and kinetic characterization". Biochim Biophys Acta. 1437 (2): 157–69. doi:10.1016/s1388-1981(99)00012-8. PMID 10064899.
  4. 1 2 "Entrez Gene: LYPLA1 lysophospholipase I".

Further reading


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