Isomigrastatin

Isomigrastatin
Names
IUPAC name
4-[7-(4-Hydroxy-5-methoxy-3-methyl-12-oxo-oxacyclododeca-6,10-dien-2-yl)-5-methyl-4-oxo-oct-6-enyl]-piperidine-2,6-dione
Identifiers
415952-70-4 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:80125
ChEMBL ChEMBL1221912
ChemSpider 13083250
PubChem 15940571
Properties
C27H39NO7
Molar mass 489.60 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Isomigrastatin is an analogue of migrastatin, an organic compound that naturally occurs in the Streptomyces platensis bacteria. Isomigrastatin has shown promise as a drug in the treatment of cancer. A laboratory synthesis was reported in 2007.[1]

References

  1. Krauss, IJ; et al. (2007). "Total Synthesis of (+)-Isomigrastatin". Angewandte Chemie. 46 (29): 5576–5579. doi:10.1002/anie.200701837. PMID 17583888.


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