Hepatitis C virus cis-acting replication element

Hepatitis C virus (HCV) cis-acting replication element (CRE)
Predicted secondary structure and sequence conservation of HepC_CRE
Identifiers
Symbol HepC_CRE
Rfam RF00260
Other data
RNA type Cis-reg
Domain(s) Viruses
SO 0000233

The Hepatitis C virus (HCV) cis-acting replication element (CRE) is an RNA element which is found in the coding region of the RNA-dependent RNA polymerase NS5B. Mutations in this family have been found to cause a blockage in RNA replication and it is thought that both the primary sequence and the structure of this element are crucial for HCV RNA replication.[1]

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