Hemslecin
Hemslecin is any of several compounds obtained from plants of the Helmseya genus, which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin F.[1][2]
The hemslecins include:
- Hemslecin A, 25-acetoxy-23,24-dihydrocucurbitacin F, from Hemsleya endecaphylla[1] and from Helmseya amabilis [2]:36
- Hemslecin B, 23,24-dihydrocucurbitacin F, from Hemsleya endecaphylla[1]
- Hemslecin C, synthesized from hemslecin A [2]:51
- Hemslecin D from Helmseya lijiangensis [2]:37
- Hemslecin E from Helmseya lijiangensis [2]:38
- Hemslecin F from Helmseya lijiangensis [2]:39
- Hemslecin G from Helmseya gigantha [2]:42
Hemslecins A and B have antibacterial properties, and have been proven to be effective against infectious diseases such as enteritis, bronchitis, acute tonsillitis, and bacillary dysentery.[1]
References
- 1 2 3 4 Jian-Chao Chen, Gao-Hong Zhang, Zhong-Quan Zhang, Ming-Hua Qiu, Yong-Tang Zheng, Liu-Meng Yang, Kai-Bei Yu (2008), "Octanorcucurbitane and Cucurbitane Triterpenoids from the Tubers of Hemsleya endecaphylla with HIV-1 Inhibitory Activity". J. Nat. Prod. volume 71, pages 153–155 doi:10.1021/np0704396
- 1 2 3 4 5 6 7 Jian Chao Chen, Ming Hua Chiu, Rui Lin Nie, Geoffrey A. Cordell and Samuel X. Qiu (2005), "Cucurbitacins and cucurbitane glycosides: structures and biological activities" Natural Product Reports, volume 22, pages 386-399 doi:10.1039/B418841C
This article is issued from Wikipedia - version of the 11/22/2013. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.