Heme arginate

Heme arginate
Identifiers
100438-92-4 YesY
MeSH Heme+arginate
PubChem 3086464
UNII R1B526117P YesY
Properties
C40H48FeN8O6+2
Molar mass 792.704
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

Heme arginate (or haem arginate) is a compound of heme and arginine used in the treatment of acute porphyrias.[1][2] This heme product is only available outside the United States and is equivalent to hematin.[3]

Heme arginate is a heme compound, whereby L-arginine is added to prevent rapid degradation. It is given intravenously, and its action of mechanism is to reduce the overproduction of δ-aminolevulinic acid, which can cause the acute symptoms in an attack of the acute porphyrias.[4]

See also

References

  1. "HAEM ARGINATE FOR THE ACUTE ATTACK OF PORPHYRIA". Porphyria South Africa.
  2. "Treatment of the Acute Attack". European Porphyria Network. Retrieved 28 August 2011.
  3. "Panhematin for Acute Porphyria". American Porphyria Foundation. Retrieved 8 July 2016.
  4. Volin, L; V Rasi; E Vahtera; R Tenhunen (1988). "Heme arginate: effects on hemostasis" (PDF). Blood Journal. 71: 625–628. Retrieved 28 August 2011.
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