H antigen
H antigen can refer to one of various types of antigens having diverse biological functions. H antigen is located on 19th chromosome :
- Also known as substance H, a precursor to each of the ABO blood group antigens, apparently present in all people except those with the Bombay Blood phenotype (see Hh antigen system)
- Histocompatibility antigen, a major factor in graft rejection. Even when Major Histocompatibility Complex genotype is perfectly matched, can cause slow rejection of a graft.[1]
- major H antigens "encode molecules that present foreign peptides to T cells"[1]
- minor H antigens "present polymorphic self peptides to T cells".[1] Includes, e.g. the H-Y antigen
- a bacterial flagellar antigen[2]
References
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