HLA-B18
major histocompatibility complex (human), class I, B18 | ||
Alleles | B*1801 | |
Alleles | B*1802 | |
Alleles | B*1803 | |
Structure (See HLA-B) | ||
Symbol(s) | HLA-B | |
EBI-HLA | B*1801 | |
EBI-HLA | B*1802 | |
EBI-HLA | B*1803 | |
Locus | chr.6 6p21.31 | |
HLA-B18 (B18) is an HLA-B serotype. The serotype identifies the more common HLA-B*18 gene products.[1] (For terminology help see: HLA-serotype tutorial) B*1801, the most common allele is at highest frequencies in Northern Italy and the Balkans, a peak frequency distribution it shares with B*3501.
Serotype
B*18 | B18 | Sample | |
allele | % | % | size (N) |
1801 | 96 | 1641 | |
1802 | 90 | 31 | |
1803 | 83 | 29 |
Allele frequencies
freq | ||
ref. | Population | (%) |
[3] | Italy North pop 1 | 16.7 |
[3] | Croatia | 11.3 |
[3] | Georgia Svaneti Svans | 11.3 |
[3] | Romanian | 11.3 |
[3] | Portugal South | 11.2 |
[3] | Singapore Riau Malay | 9.9 |
[3] | Bulgaria | 9.1 |
[3] | Israel Arab Druse | 8.5 |
[3] | Azores Central Islands | 8.0 |
[3] | Portugal Centre | 8.0 |
[3] | Finland | 7.8 |
[3] | Azores Santa Maria and Sao Miguel | 7.7 |
[3] | Czech Republic | 7.5 |
[3] | India Jalpaiguri Toto | 7.5 |
[3] | Iran Baloch | 7.1 |
[3] | Philippines Ivatan | 7.0 |
[3] | Thailand | 6.7 |
[3] | Tunisia | 6.7 |
[3] | Portugal North | 6.5 |
[3] | Zimbabwe Harare Shona | 6.4 |
[3] | Madeira | 6.2 |
[3] | Mexico Mestizos | 6.1 |
[3] | Kenya | 5.9 |
[3] | Belgium | 5.1 |
[3] | Morocco Nador Metalsa Class I | 5.1 |
[3] | Singapore Javanese Indonesians | 5.1 |
[3] | Israel Ashkenazi and Non Ashkenazi Jews | 5.0 |
[3] | Uganda Kampala | 5.0 |
[3] | Kenya Nandi | 4.8 |
[3] | Oman | 4.7 |
[3] | Georgia Tibilisi Georgians | 4.6 |
[3] | Bulgaria Gipsy | 4.5 |
[3] | France South East | 4.3 |
[3] | Kenya Luo | 4.3 |
[3] | Ireland South | 4.2 |
[3] | Russia Arkhangelsk Pomors | 4.0 |
[3] | Azores Terceira Island | 3.9 |
[3] | Guinea Bissau | 3.8 |
[3] | India New Delhi | 3.8 |
[3] | Spain Eastern Andalusia Gipsy | 3.5 |
[3] | Australia New South Wales | 3.4 |
[3] | Georgia Tibilisi Kurds | 3.4 |
[3] | Zambia Lusaka | 3.4 |
[3] | Cameroon Yaounde | 2.7 |
[3] | Senegal Niokholo Mandenka | 2.7 |
[3] | Cameroon Beti | 2.3 |
[3] | Ivory Coast Akan Adiopodoume | 2.3 |
[3] | Sudanese | 2.3 |
[3] | Saudi Arabia Guraiat and Hail | 2.2 |
[3] | South African Natal Zulu | 2.0 |
[3] | Thailand | 2.0 |
[3] | India Mumbai Marathas | 1.9 |
[3] | New Caledonia | 1.9 |
[3] | Papua New Guinea Wanigela | 1.5 |
[3] | Cameroon Bamileke | 1.3 |
References
- ↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
- ↑ derived from IMGT/HLA
- 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in
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