FAM3C
| FAM3C | |||||||||||||||||
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| Identifiers | |||||||||||||||||
| Aliases | FAM3C, ILEI, GS3786, family with sequence similarity 3 member C | ||||||||||||||||
| External IDs | MGI: 107892 HomoloGene: 8926 GeneCards: FAM3C | ||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||
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| Location (UCSC) | Chr 7: 121.35 – 121.4 Mb | Chr 6: 22.31 – 22.36 Mb | |||||||||||||||
| PubMed search | [1] | [2] | |||||||||||||||
| Wikidata | |||||||||||||||||
| View/Edit Human | View/Edit Mouse |
Protein FAM3C is a protein that in humans is encoded by the FAM3C gene.[3][4]
Function
This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. Alternate transcriptional splice variants which encode the same protein have been characterized.[4]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Zhu Y, Xu G, Patel A, McLaughlin MM, Silverman C, Knecht K, Sweitzer S, Li X, McDonnell P, Mirabile R, Zimmerman D, Boyce R, Tierney LA, Hu E, Livi GP, Wolf B, Abdel-Meguid SS, Rose GD, Aurora R, Hensley P, Briggs M, Young PR (Aug 2002). "Cloning, expression, and initial characterization of a novel cytokine-like gene family". Genomics. 80 (2): 144–50. doi:10.1006/geno.2002.6816. PMID 12160727.
- 1 2 "Entrez Gene: FAM3C family with sequence similarity 3, member C".
Further reading
- "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241
. PMID 12477932. - Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Fortna A, Kim Y, MacLaren E, et al. (2006). "Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution". PLoS Biol. 2 (7): E207. doi:10.1371/journal.pbio.0020207. PMC 449870. PMID 15252450.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Mauri P, Scarpa A, Nascimbeni AC, et al. (2006). "Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers". FASEB J. 19 (9): 1125–7. doi:10.1096/fj.04-3000fje. PMID 15985535.
- Grønborg M, Kristiansen TZ, Iwahori A, et al. (2006). "Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach". Mol. Cell Proteomics. 5 (1): 157–71. doi:10.1074/mcp.M500178-MCP200. PMID 16215274.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Guo J, Cheng H, Zhao S, Yu L (2006). "GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases". FEBS Lett. 580 (2): 581–4. doi:10.1016/j.febslet.2005.12.076. PMID 16406369.
- Waerner T, Alacakaptan M, Tamir I, et al. (2006). "ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells". Cancer Cell. 10 (3): 227–39. doi:10.1016/j.ccr.2006.07.020. PMID 16959614.
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