Epi-isozizaene synthase
| Epi-isozizaene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.37 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Epi-isozizaene synthase (EC 4.2.3.37, SCO5222 protein) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-epi-isozizaene-forming).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate (+)-epi-isozizaene + diphosphate
This enzyme requires Mg2+ for activity.
References
- ↑ Lin, X.; Hopson, R.; Cane, D.E. (2006). "Genome mining in Streptomyces coelicolor: molecular cloning and characterization of a new sesquiterpene synthase". J. Am. Chem. Soc. 128 (18): 6022–6023. doi:10.1021/ja061292s. PMID 16669656.
- ↑ Zhao, B.; Lin, X.; Lei, L.; Lamb, D.C.; Kelly, S.L.; Waterman, M.R.; Cane, D.E. (2008). "Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2)". J. Biol. Chem. 283: 8183–8189. doi:10.1074/jbc.M710421200. PMC 2276382
. PMID 18234666.
External links
- Epi-isozizaene synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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