Discodermia dissoluta

Discodermia dissoluta
Scientific classification
Kingdom: Animalia
Phylum: Porifera
Class: Demospongiae
Order: Tetractinellida
Family: Theonellidae
Genus: Discodermia
Species: D. dissoluta
Binomial name
Discodermia dissoluta
(Schmidt, 1880)[1]

Discodermia dissoluta is a deep-water marine sponge found in the Eastern, Southern, and Southwestern Caribbean, and in the Greater Antilles.[1][2]

D. dissoluta is of interest from a drug discovery perspective because it produces (+)-discodermolide, a polyketide natural product with immunosuppressive and antiproliferative properties.[3]

References

  1. 1 2 "Discodermia dissoluta Schmidt, 1880". WoRMS. 2015. Retrieved 6 Feb 2016.
  2. Brück WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ (2008). "Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp.". The ISME Journal. 2: 335–339. doi:10.1038/ismej.2007.91.
  3. Singh R, Sharma M, Joshi P, Rawat DS (2008). "Clinical status of anti-cancer agents derived from marine sources". Anticancer Agents in Medicinal Chemistry. 8 (6): 603–617. doi:10.2174/187152008785133074. PMID 18690825.


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