DDX41

DDX41
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases DDX41, ABS, MPLPF, DEAD-box helicase 41
External IDs MGI: 1920185 HomoloGene: 9431 GeneCards: DDX41
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

51428

72935

Ensembl

ENSG00000183258

ENSMUSG00000021494

UniProt

Q9UJV9

Q91VN6

RefSeq (mRNA)

NM_016222
NM_001321732
NM_001321830

NM_134059

RefSeq (protein)

NP_057306.2
NP_001308661.1
NP_001308759.1

NP_598820.2

Location (UCSC) Chr 5: 177.51 – 177.52 Mb Chr 13: 55.53 – 55.54 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Probable ATP-dependent RNA helicase DDX41 is an enzyme that in humans is encoded by the DDX41 gene.[3][4]

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Irion U, Leptin M (Feb 2000). "Developmental and cell biological functions of the Drosophila DEAD-box protein abstrakt". Curr Biol. 9 (23): 1373–81. doi:10.1016/S0960-9822(00)80082-2. PMID 10607561.
  4. 1 2 "Entrez Gene: DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41".

Further reading


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