Carbylamine reaction
The carbylamine reaction, also known as Hoffman's isocyanide test is a chemical test for detection of primary amines.[1] In this reaction, the analyte is heated with alcoholic potassium hydroxide and chloroform. If a primary amine is present, the isocyanide (carbylamine) is formed which are foul smelling substances.
For example, the reaction with ethylamine:
The reaction with aniline:
The carbylamine test does not give a positive reaction with secondary and tertiary amines.
References
This article is issued from Wikipedia - version of the 9/21/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.