BRE (gene)

BRE
Identifiers
Aliases BRE, BRCC4, BRCC45, brain and reproductive organ-expressed (TNFRSF1A modulator)
External IDs MGI: 1333875 HomoloGene: 3604 GeneCards: BRE
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

9577

107976

Ensembl

ENSG00000158019

ENSMUSG00000052139

UniProt

Q9NXR7

Q8K3W0

RefSeq (mRNA)

NM_144541
NM_181279
NM_181280
NM_181281
NM_181282

RefSeq (protein)

NP_653124.1
NP_851796.1
NP_851797.1
NP_851798.1
NP_851799.1

Location (UCSC) Chr 2: 27.89 – 28.34 Mb Chr 5: 31.7 – 32.08 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

BRCA1-A complex subunit BRE is a protein that in humans is encoded by the BRE gene.[3][4][5]

Interactions

BRE (gene) has been shown to interact with:

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ Gu C, Castellino A, Chan JY, Chao MV (Sep 1998). "BRE: a modulator of TNF-alpha action". FASEB Journal. 12 (12): 1101–8. PMID 9737713.
  4. ↑ Li L, Yoo H, Becker FF, Ali-Osman F, Chan JY (Jan 1995). "Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid". Biochemical and Biophysical Research Communications. 206 (2): 764–74. doi:10.1006/bbrc.1995.1108. PMID 7826398.
  5. ↑ "Entrez Gene: BRE brain and reproductive organ-expressed (TNFRSF1A modulator)".
  6. 1 2 3 4 5 6 Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R (Nov 2003). "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair". Molecular Cell. 12 (5): 1087–99. doi:10.1016/s1097-2765(03)00424-6. PMID 14636569.
  7. 1 2 Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3: 89. doi:10.1038/msb4100134. PMC 1847948Freely accessible. PMID 17353931.
  8. ↑ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading

  • Miao J, Panesar NS, Chan KT, Lai FM, Xia N, Wang Y, Johnson PJ, Chan JY (Apr 2001). "Differential expression of a stress-modulating gene, BRE, in the adrenal gland, in adrenal neoplasia, and in abnormal adrenal tissues". The Journal of Histochemistry and Cytochemistry. 49 (4): 491–500. doi:10.1177/002215540104900409. PMID 11259452. 
  • Ching AK, Li PS, Li Q, Chan BC, Chan JY, Lim PL, Pang JC, Chui YL (Nov 2001). "Expression of human BRE in multiple isoforms". Biochemical and Biophysical Research Communications. 288 (3): 535–45. doi:10.1006/bbrc.2001.5801. PMID 11676476. 
  • Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R (Nov 2003). "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair". Molecular Cell. 12 (5): 1087–99. doi:10.1016/S1097-2765(03)00424-6. PMID 14636569. 
  • Li Q, Ching AK, Chan BC, Chow SK, Lim PL, Ho TC, Ip WK, Wong CK, Lam CW, Lee KK, Chan JY, Chui YL (Dec 2004). "A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway". The Journal of Biological Chemistry. 279 (50): 52106–16. doi:10.1074/jbc.M408678200. PMID 15465831. 
  • Chan BC, Li Q, Chow SK, Ching AK, Liew CT, Lim PL, Lee KK, Chan JY, Chui YL (Jan 2005). "BRE enhances in vivo growth of tumor cells". Biochemical and Biophysical Research Communications. 326 (2): 268–73. doi:10.1016/j.bbrc.2004.11.013. PMID 15582573. 
  • Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
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