Anserine

For the subfamily of waterfowl, see Anserinae.
Anserine
Names
IUPAC name
(2S)-2-[(3-Amino-1-oxopropyl)amino]-3-(3-methyl-4-imidazolyl)propanoic acid
Other names
beta-Alanyl-N(pi)-methyl-L-histidine
Identifiers
584-85-0 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:18323 YesY
ChEMBL ChEMBL448301 YesY
ChemSpider 100482 YesY
ECHA InfoCard 100.008.679
KEGG C01262 YesY
PubChem 112072
Properties
C10H16N4O3
Molar mass 240.25904 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Anserine (β-alanyl-N-methylhistidine) is a dipeptide containing β-alanine and 1-methylhistidine,[1] which can be found in the skeletal muscle and brain of mammals[2] and birds.

The pKa of the imidazole ring of histidine, when contained in anserine, is 7.04, making it an effective buffer at physiologic pH.[3]

See also

References

  1. Biochemistry, Garrett & Grisham, pg. 46
  2. Quantitative studies of carnosine and anserine in mammalian muscle. 1938 (pdf)
  3. Biochemistry, Garrett & Grisham
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