Allene-oxide cyclase
allene-oxide cyclase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC number | 5.3.99.6 | ||||||||
CAS number | 118390-59-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
|
In enzymology, an allene-oxide cyclase (EC 5.3.99.6) is an enzyme that catalyzes the chemical reaction
- (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate (15Z)-12-oxophyto-10,15-dienoate
Hence, this enzyme has one substrate, (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate, and one product, (15Z)-12-oxophyto-10,15-dienoate.
This enzyme belongs to the family of isomerases, specifically a class of other intramolecular oxidoreductases. The systematic name of this enzyme class is (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing).
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1Z8K, 1ZVC, 2BRJ, 2DIO, 2GIN, and 2Q4I.
References
- Hamberg M (1988). "Biosynthesis of 12-oxo-10,15(Z)-phytodienoic acid: identification of an allene oxide cyclase". Biochem. Biophys. Res. Commun. 156 (1): 543–50. doi:10.1016/S0006-291X(88)80876-3. PMID 3178850.
This article is issued from Wikipedia - version of the 4/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.