Adamalysin

Adamalysin
Identifiers
EC number 3.4.24.46
CAS number 74812-51-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Adamalysin (EC 3.4.24.46, Crotalus adamanteus metalloendopeptidase, proteinase I and II, Crotalus adamanteus venom proteinase II, adamalysin II) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Phe1-Val, His5-Leu, His10-Leu, Ala14-Leu, Leu15-Tyr, and Tyr16-Leu of insulin B chain

This enzyme is present in the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

See also

References

  1. Kurecki, T.; Laskowski, M. Sr.; Kress, L.F. (1978). "Purification and some properties of two proteinases from Crotalus adamanteus venom that inactivate human α1-proteinase inhibitor". J. Biol. Chem. 253: 8340–8345. PMID 309470.

External links

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